影片是2015年推出的小黄人独立电影《小黄人大眼萌》的直接前传。作为《神偷奶爸》的衍生作品，讲述了小黄人们在“前格鲁”时代为其他主人服务的经历，不过少年格鲁曾经出现在这部衍生电影里，续集将围绕他与小黄人们结缘的过程展开。这部影片讲述了小黄人与小老板格鲁的“相遇元年”的故事，小黄人初识心存终极志向的小老板，建立起了深厚情谊，并与几个超级恶霸展开了抗衡，最终救出身处险境的小老板。“贱萌天团”小黄人全员出动，还有一位呆萌的新成员——牙套仔奥豆的加入。《小黄人大眼萌2》来到格鲁的少年时代，带来他与小黄人的结缘往事。小黄人们通过应聘，成为“坏蛋梦想家”格鲁的助手，但他们从“极恶六天王”手中盗走的宝石，却被小黄人新成员奥豆弄丢，由此引发了一连串奇趣的故事。
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